Fluid Mixing Chips
In the past two decades, microfluidic devices have been widely applied to analytical chemistry, clinical diagnosis, environmental monitoring, and food analysis. However, the small channel size in the microfluidic system and the limited range of achievable speeds in operation result in a low Reynolds number (Re), so the flow state is mostly laminar. In this laminar flow, traditional turbulent mixing cannot occur between the two liquids, making the mixing of microfluidics a challenge.
Figure.1 Schematic diagram of on-chip particle washing using coflow of viscoelastic fluid and a Newtonian fluid. (Yuan D, et al. 2017)
Controllable rapid mixing is essential for the subsequent practical development of microfluidics and lab-on-a-chip equipment, which is often used for assays involving many reagents and samples. Based on this, various research groups at Alfa Chemistry have developed and studied different microfluidic mixing technologies. We can provide you with customized services of fluid mixing chips and support your microfluidic research. Please contact us for more information.
About Alfa Chemistry's Fluid Mixing Chips
In laminar flow, mixing occurs only through molecular diffusion, so one way to increase mixing between liquids is to enhance the diffusion effect between samples. We can flow the sample through various holes incorporated into the microfluidic chip, or we can separate the sample between multiple smaller channels. Another method is to increase the contact area and contact time between the mixed reagents. In this case, we design the channel geometry in a way that can increase the contact area or/and contact time between the reagents involved in the mixing process.
Alfa Chemistry has designed three different fluid mixing chips to support your research. You can choose one or customize your own according to your needs.
- Name: Fluid Mixing Chip a, b, or c
- Material: PDMS
- Are there accessories: None
- How to use: Use a syringe or pipette to inject liquid
- Specifications: Tube width 1000μm, tube depth 1000μm (a); tube width 500μm, tube depth 500μm (b); tube width 500μm, tube depth 500μm (c)
Advantages of Our Fluid Mixing Chips
The advantages of our fluid mixing chips include, but are not limited to, the following:
- Thin glass slide option
- Extended chip life
- High connection density
- Good microscope access
- Adapt to various PDMS equipment heights
- No need to punch holes in PDMS to get liquid
References
- Kwon S K, et al. (2008). "Sensing Cyanide Ion via Fluorescent Change and Its Application to The Microfluidic System." Tetrahedron Letters, V. 49(26): 4102-4105.
- Yuan D, et al. (2017). "On-Chip Microparticle and Cell Washing Using Coflow of Viscoelastic Fluid and Newtonian Fluid." Analytical Chemistry. 89(17): 9574-9582.
Our products and services are for research use only.
