LNP Synthetic Chips
Lipid Nanoparticle (LNP) is one of the more advanced gene delivery vectors. It overcomes the delivery barriers in gene drug discovery and development by allowing rapid delivery of nucleic acids into biological cells, widely used in gene editing, vaccine development, tumor immunization, and rare disease therapies.
Among the numerous methods of LNP synthesis, microfluidics is far ahead. It enables extremely fine control of the final properties of LNP and can handle both very small and large amounts of liquid, making it useful throughout the drug development process. Alfa Chemistry offers LNP synthesis chips that enable an efficient and precise LNP preparation process.
Specification
| Item/Catalog | MF-MC18 |
| Chip material | COC |
| Chip dimensions (L×W) | 62.2×41.3 mm |
| Channel width | 350-700 μm |
| Recommended total flow rate | 12 mL/min |
| Max total flow rate | 24 mL/min |
| Pressure tolerance range | ＜50 bar |
Advantages
The advantages of microfluidic LNP synthesis chips mainly include:
- They can reduce mixing time for high throughput and continuous production.
- They can improve particle homogeneity with polymer dispersion index as low as 0.02.
- They enable monodisperse nanoparticles of multiple particle sizes through precise flow rate control.
- They enable integrated and automated production of nanoparticles with excellent reproducibility of multiple preparations.
Why Choose Us
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Versatility
We offer a range of ready-to-use functional chips to make them easier to apply in areas such as life sciences, diagnostics and chemical analysis.
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Reliability
With unique expertise and rich technical accumulation in microfluidic manufacturing, our team is able to provide top-quality solutions to our customers.
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High quality
Using advanced micro-nanofluidic processing and photolithography to precisely control the channel size and structure shape to ensure the stability and reliability of the chip.
Dedicated to the development and manufacture of microfluidic devices, Alfa Chemistry is your trusted partner. If you don't find what you are looking for, please contact us. We also provide customized service according to your detailed requirements.
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