LNP Synthetic Chips

Lipid Nanoparticle (LNP) is one of the more advanced gene delivery vectors. It overcomes the delivery barriers in gene drug discovery and development by allowing rapid delivery of nucleic acids into biological cells, widely used in gene editing, vaccine development, tumor immunization, and rare disease therapies.

Among the numerous methods of LNP synthesis, microfluidics is far ahead. It enables extremely fine control of the final properties of LNP and can handle both very small and large amounts of liquid, making it useful throughout the drug development process. Alfa Chemistry offers LNP synthesis chips that enable an efficient and precise LNP preparation process.


Chip materialCOC
Chip dimensions (L×W)62.2×41.3 mm
Channel width350-700 μm
Recommended total flow rate12 mL/min
Max total flow rate24 mL/min
Pressure tolerance range<50 bar


The advantages of microfluidic LNP synthesis chips mainly include:

LNP Synthetic Chips

  • They can reduce mixing time for high throughput and continuous production.
  • They can improve particle homogeneity with polymer dispersion index as low as 0.02.
  • They enable monodisperse nanoparticles of multiple particle sizes through precise flow rate control.
  • They enable integrated and automated production of nanoparticles with excellent reproducibility of multiple preparations.

Why Choose Us

Dedicated to the development and manufacture of microfluidic devices, Alfa Chemistry is your trusted partner. If you don't find what you are looking for, please contact us. We also provide customized service according to your detailed requirements.

Our products and services are for research use only.

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